How do/has opioids impact/ed humans historically, socially, and culturally?

Description

The reasearch should be like  Introduction: Origins of opioids and lead into heroin and fentanyl which are the two big substances that we mostly know. Next cover the  Cultural/Anthropological aspect of it as of: Discover how opioids changed the world historically, how it has shaped the world today and how the world would be different without opioids. It is a research paper that focus mostly on the historical and cultural influence of opioids in the world, don’t go into the chemistry etc…  I am looking for someone who can talk about the opioids war and it’s introduction to the US and someone who can imagine a world without it ! here are some links to help:  https://en.wikipedia.org/wiki/Opium_Wars#:~:text=The%20First%20Opium%20War%2C%20fought,and%20France%2C%201856%E2%80%931860. https://dualdiagnosis.org/infographics/history-of-the-opioid-epidemic/ http://www.druglibrary.org/schaffer/heroin/opiwar1.htm